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MachineCodex has released a new public beta of MachineHead, an alternative media player for OS X that lets you slow it down, pitch it up, loop it, warp it, manipulate it, slap it up, flip it, rub it down - oh no!
Features:

Pitch Shifting: -1200 to +1200Hz
Time Shifting: 1/4x to 4x speed
Opens most audio files
Opens [...]

Shuriken has released Shredder, a free VST sampler for Windows & Mac designed to be easy to use and fun to play with. It has 12 slots for samples that are controllable via MIDI notes or automatable parameters as well as the GUI.

Neuenberger have released an alpha version of their JellyFilter v2.0 freeware polyphonic lead synth for Windows.
Technical details:

Polyphony / Timbrality: 4 voices per channel, 16 channels.
Oscillators: 2 Oscillators with Controllable Unisono per Osc: Saw, Sine, Square, Pulse with PWM, Noise.
Filter: 24dB LowPass and Bandpass with resonance, Highpass, envelope amount and cutoff, possibility for self-resonance (protect [...]

The Institute for Computer Music and Sound Technology has released an open-source Windows framework for developing virtual synthesizers:
SynStart is a simple and straightforward free open source framework for audio programming in C++. It embeds all the interfaces and book keeping routines required to build stand-alone real-time sound generators for the Windows platform: A polyphonic [...]

ndc Plugs has released Fragmental, a free Windows VST plug-in.
Description:
A complex multi-fx plugin incorporating a delay, granulator, three phase vocoder effects, a reversinator, and three types of modulation source. Incorporates a very flexible routing scheme capable of serial and parallel effects routings, and a new kind of modulation routing based on a kind of pie [...]

De La Mancha has released a new free VST synth for Windows, Entropy.Entropy is a 3 osc subtractive synth with a set of pitch randomising options to generate melodies “all on it’s ownsome”.

Maizesoft has introduced Maize Sampler, a sample engine that lets you share your samples with musicians around the world.
Features:

Propagation (VSTi export) with pre-defined UI styles
Keyswitching between 12 layers
Disk-streaming
Sample-mapping, velocity layering
16 channels, 4 stereo output, 32 polyphonies
Supports 8, 16, 24 bit sample rate
Built-in simple reverb and EQ
Both VSTi and Standalone modes
Comes with a Soundfont to Maize [...]

Nexoft’s LoopAZoid is a free tool for playing one-shot samples in your songs.
One instance holds up to 48 different samples, which can be freely assigned to up to 96 different MIDI notes - two each, for forward & reverse playback. Each of the 48 sample channels has a pre-defined MIDI note attached; triggering these in [...]