VstCafe demonstrates how to make an awesome progressive house lead:

This tutorial shows how to create (with Synapse Toxic II 2.5 vst plugin – btw. it’s a killer synth for such low price) a simple, progressive house lead similar to those well known kaskade, dmau leads.

As you can see, I didn’t use internal delay / reverb unit. I used external – Ableton effects such as reverb, ping pong delay, EQ and compressor (sidechaining) – really nothing special.